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Contraindicated. CYP3A4 is answerable for the formation and elimination of cariprazine's Energetic metabolites. The effect of CYP3A4 inducers on cariprazine publicity has not been evaluated plus the Web influence is unclear.pentobarbital decreases amounts of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. S